Article
Intrafamilial phenotypic expression of autosomal dominant polycystic kidney disease.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 May 1992
Milutinovic J, Rust P F, Fialkow P J, Agodoa L Y, Phillips L A, Rudd T G, Sutherland S
Abstract excerpt
It has been suggested that the clinical expression of autosomal dominant polycystic kidney disease (ADPKD) is uniform among individuals of a given family. To test this hypothesis, intrafamilial variations in ages at onset of first symptoms, types of first symptoms, serum creatinine concentrations, and renal sizes were evaluated in 131 patients with ADPKD from 36 unrelated families. These parameters were compared...
Topics
- Adolescent
- Adult
- Creatinine
- Family
- Female
- Humans
- Kidney
- Male
- Middle Aged
- Phenotype
- Polycystic Kidney, Autosomal Dominant