Article
Cerebrospinal fluid profile in frontotemporal dementia and Alzheimer's disease.
Annals of neurology - 1 May 2005
Grossman Murray, Farmer Jennifer, Leight Susan, Work Melissa, Moore Peachie, Van Deerlin Vivianna, Pratico Domenico, Clark Christopher M, Coslett H Branch, Chatterjee Anjan, Gee James, Trojanowski John Q, Lee Virginia M-Y
Abstract excerpt
We assessed cerebrospinal fluid (CSF) levels of tau and other biomarkers of neurodegenerative disease. CSF tau levels vary widely in reports of frontotemporal dementia (FTD). CSF samples were assayed for tau, amyloid beta1-42 (A1-42), and the isoprostane 8,12-iso-iPF2a-VI (iP) prospectively in 64 patients with FTD, retrospectively in 26 autopsied cases with FTD or Alzheimer's disease (AD), and in 13 healthy...
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