Article
Prophylaxis of hepatitis B virus recurrence after liver transplantation in carriers of lamivudine-resistant mutants.
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society - 1 May 2005
Marzano Alfredo, Lampertico Pietro, Mazzaferro Vincenzo, Carenzi Silvia, Vigano Mauro, Romito Raffaele, Pulvirenti Andrea, Franchello Alessandro, Colombo Massimo, Salizzoni Mauro, Rizzetto Mario
Abstract excerpt
The combination of lamivudine and hepatitis B immunoglobulin (HBIG) reduces the risk of hepatitis B virus (HBV) recurrence after liver transplantation (LT). However, the efficacy of this strategy and the need for combined therapy with adefovir dipivoxil (ADV) in patients who select lamivudine-resistant strains (YMDD) before surgery is still unknown. Twenty-two patients treated with lamivudine (LAM) who underwent...
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