Article
Hepatitis-B-virus resistance to lamivudine given for recurrent infection after orthotopic liver transplantation
1 Jan 1997
Abstract excerpt
BACKGROUND: Orthotopic liver transplantation for end-stage hepatitis-B-virus (HBV) infection is commonly complicated by recurrence of HBV. Lamivudine, a cytosine nucleoside analogue, has been shown to suppress HBV infection. We report the development of resistance to lamivudine in three patients who underwent transplantation for end-stage liver disease secondary to hepatitis B. METHODS: Two of the patients...
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