Article
No hepatitis recurrence using combination prophylaxis in HBV-positive liver transplant recipients with YMDD mutants.
Transplant international : official journal of the European Society for Organ Transplantation - 1 Feb 2005
Caccamo Lucio, Romeo Raffaella, Rossi Giorgio, Maggioni Mauro, Radice Ferdinando, Lunghi Giovanna, Colombo Massimo, Fassati Luigi R
Abstract excerpt
Recurrence of hepatitis B impairs the outcome of liver transplantation (OLT). In serum hepatitis B virus (HBV)-DNA-positive recipients, prophylaxis using lamivudine and immunoglobulins (HBIg) reduces the risk of recurrence, but it is undefined whether this regimen also protects candidates with YMDD mutants. Seventeen OLT viraemic candidates received pre-emptive lamivudine followed by post-OLT prophylaxis with...
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