Article
Dysferlin Interacts with Affixin (β-Parvin) at the Sarcolemma
1 Apr 2005
Abstract excerpt
The dysferlin gene is defective in Miyoshi myopathy (MM) and limb girdle muscular dystrophy type 2B (LGMD2B). Dysferlin is a sarcolemmal protein that is implicated in calcium-dependent membrane repair. Affixin (beta-parvin) is a novel, integrin-linked kinase-binding protein that is involved in the linkage between integrin and the cytoskeleton. Here we show that affixin is a dysferlin binding protein that...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
