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Article

An efficient Monte Carlo method for estimating Ne from temporally spaced samples using a coalescent-based likelihood.

Genetics - 1 Jun 2005

Anderson Eric C

Abstract excerpt

This article presents an efficient importance-sampling method for computing the likelihood of the effective size of a population under the coalescent model of Berthier et al. Previous computational approaches, using Markov chain Monte Carlo, required many minutes to several hours to analyze small data sets. The approach presented here is orders of magnitude faster and can provide an approximation to the...

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Identifiers

PMID: 15834143
DOI: 10.1534/genetics.104.038349
PMCID: PMC1450415

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