Article
beta-Lactam antibiotic-induced release of free endotoxin: in vitro comparison of penicillin-binding protein (PBP) 2-specific imipenem and PBP 3-specific ceftazidime.
The Journal of infectious diseases - 1 Jun 1992
Jackson J J, Kropp H
Abstract excerpt
The relative effects of two beta-lactam antibiotics, penicillin-binding protein (PBP) 2-specific imipenem and PBP 3-specific ceftazidime, upon in vitro induction of lipopolysaccharide (LPS) release were investigated against smooth- and rough-LPS mutant isolates of Pseudomonas aeruginosa. Free LPS...
Topics
- Animals
- Bacterial Proteins
- Carrier Proteins
- Ceftazidime
- Edetic Acid
- Female
- Hexosyltransferases
- Imipenem
- Lipopolysaccharides
- Mice
- Microbial Sensitivity Tests
- Multienzyme Complexes
- Muramoylpentapeptide Carboxypeptidase
- Mutation
- Penicillin-Binding Proteins
- Peptidyl Transferases
- Pseudomonas aeruginosa