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Article

[Detection of a non-standard mutation in the ret protoncogene by site directed mutagenesis].

Medicina - 1 Jan 2005

Real Sebastián, Gómez Laura, Perinetti Héctor, Mayorga Luis S, Pusiol Eduardo, Roqué María

Abstract excerpt

MEN2A is an autosomic dominant disease, characterized by medullary thyroid cancer, pheochromocytoma and parathyroid hyperplasia. Mutations in the ret proto-oncogene are associated with this disease, with almost 100% of penetrance. The gene, situated on chromosome 10q11.2, codes for a transmembrane protein with a tyrosinkinase-like receptor function. Mutations that affect its extracellular domain, stimulate...

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Share to Electrophoresis, Polyacrylamide Gel
Share to Multiple Endocrine Neoplasia Type 2a

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15830792

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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