Article
[Ret-protooncogene mutation, verified by molecular genetic methods, in a Hungarian MEN Type 2a family].
Orvosi hetilap - 14 Feb 1999
Igaz P, Rácz K, Tóth M, Cserepes E, Esik O, Kiss R, Perner F, Gláz E, Tulassay Z
Abstract excerpt
Multiple endocrine neoplasia Type 2 (MEN2) is a hereditary tumour syndrome characterized by the association of medullary thyroid cancer, phaeochromocytoma and hyperparathyroidism. It is inherited as an autosomal dominant trait. During the past few years the cloning of the gene responsible for the syndrome, the ret protooncogene, made the molecular genetic diagnosis of the disease possible. In this study we...
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