Article
[Genetic analysis of RET mutations in families with multiple endocrine neoplasia type II in the community of Murcia].
Medicina clinica - 15 May 1999
Pomares Gómez F J, Bernabé Espinosa M J, Matías-Guiu Guía X, Rodríguez González J M, Soriano Palao J, Sola Pérez J, Carbonell Meseguer P, Parrilla Paricio P, Tébar Massó F J
Abstract excerpt
BACKGROUND: Multiple endocrine neoplasia type 2 (MEN 2) syndromes are inherited following an autosomal dominant pattern. RET protooncogen mutations have been associated with MEN 2. The identification of these mutations enables us to diagnose MEN 2. The objectives were to recognize RET mutations and gene carriers in the area of Murcia and to sep up the relationship between genotype and phenotype. PATIENTS AND...
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