Article
Coronin-1 function is required for phagosome formation.
Molecular biology of the cell - 1 Jul 2005
Yan Ming, Collins Richard F, Grinstein Sergio, Trimble William S
Abstract excerpt
Coronin-1 is an actin-associated protein whose function in actin dynamics has remained obscure. All coronin proteins have a variable N-terminal domain, followed by WD repeats and a C-terminal coiled-coil dimerization domain. Transfection of coronin-1-GFP into RAW 264.7 cells revealed that coronin rapidly and transiently associates with the phagosome. To determine if coronin is involved in mammalian phagocytosis...
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