Article
The association between the T102C polymorphism of the HTR2A serotonin receptor gene and HDL cholesterol level in Koreans.
Journal of biochemistry and molecular biology - 31 Mar 2005
Choi Jin-Ho, Zhang Shu-Ying, Park Kyung-Woo, Cho Young-Seok, Oh Byung-Hee, Lee Myoung-Mook, Park Young-Bae, Kim Hyo-Soo
Abstract excerpt
5-HT2A is one of major serotonin receptor that is involved in the action of serotonin-targeting drugs. Previous clinical studies have shown an unexpected association between lower cholesterol level and psychiatric diseases, in which T102C polymorphism of HTR2A, gene of 5-HT2A serotonin receptor, might be involved. Therefore, we hypothesized a potential association between lower cholesterol level and T102C...
Topics
- Case-Control Studies
- Cholesterol, HDL
- Female
- Gene Frequency
- Genotype
- Humans
- Korea
- Lipids
- Male
- Middle Aged
- Polymorphism, Genetic
- Receptor, Serotonin, 5-HT2A
