Article
Intracellular selection, conversion bias, and the expected substitution rate of organelle genes.
Genetics - 1 Apr 1992
Walsh J B
Abstract excerpt
A key step in the substitution of a new organelle mutant throughout a population is the generation of germ-line cells homoplasmic for that mutant. Given that each cell typically contains multiple copies of organelles, each of which in turn contains multiple copies of the organelle genome, processes akin to drift and selection in a population are responsible for producing homoplasmic cells. This paper examines the...
Topics
- DNA Replication
- Gene Frequency
- Genes
- Models, Genetic
- Models, Statistical
- Mutation
- Organelles
- Probability
- Selection, Genetic