Article
Mutation pressure, drift, and the pace of molecular coevolution.
Proceedings of the National Academy of Sciences of the United States of America - 4 Jul 2023
Lynch Michael
Abstract excerpt
Most aspects of the molecular biology of cells involve tightly coordinated intermolecular interactions requiring specific recognition at the nucleotide and/or amino acid levels. This has led to long-standing interest in the degree to which constraints on interacting molecules result in conserved vs. accelerated rates of sequence evolution, with arguments commonly being made that molecular coevolution can proceed...
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