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Comparing Genomes of <i>Helicobacter pylori</i> Strains from the High-Altitude Desert of Ladakh, India

1 Apr 2005

Abstract excerpt

The genomic diversity of Helicobacter pylori from the vast Indian subcontinent is largely unknown. We compared the genomes of 10 H. pylori strains from Ladakh, North India. Molecular analysis was carried out to identify rearrangements within and outside the cag pathogenicity island (cag PAI) and DNA sequence divergence in candidate genes. Analyses of virulence genes (such as the cag PAI as a whole, cagA, vacA,...

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PMID: 15814963
DOI: 10.1128/jcm.43.4.1538-1545.2005

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