Article
High prevalence of Plasmodium falciparum pfcrt K76T mutation in pregnant women taking chloroquine prophylaxis in Senegal.
The Journal of antimicrobial chemotherapy - 1 May 2005
Bertin Gwladys, Ndam Nicaise Tuikue, Jafari-Guemouri Sayeh, Fievet Nadine, Renart Emily, Sow Sokhna, Le Hesran Jean-Yves, Deloron Philippe
Abstract excerpt
OBJECTIVES: The risk of malaria infection is increased during pregnancy, and many countries recommend chloroquine prophylaxis in pregnant women, despite Plasmodium falciparum chloroquine resistance. Chloroquine resistance is associated with the pfcrt gene K76T mutation. The aim of this study was to compare the prevalence rate of pfcrt T76 mutation in P. falciparum isolates from infected pregnant and non-pregnant...
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