Article
Mutants of FtsZ targeting the protofilament interface: effects on cell division and GTPase activity.
Journal of bacteriology - 1 Apr 2005
Redick Sambra D, Stricker Jesse, Briscoe Gina, Erickson Harold P
Abstract excerpt
The bacterial cell division protein FtsZ assembles into straight protofilaments, one subunit thick, in which subunits appear to be connected by identical bonds or interfaces. These bonds involve the top surface of one subunit making extensive contact with the bottom surface of the subunit above it. We have investigated this interface by site-directed mutagenesis. We found nine bottom and eight top mutants that...
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