Article
A set of ftsZ mutants blocked at different stages of cell division in Caulobacter.
Molecular microbiology - 1 Apr 2001
Wang Y, Jones B D, Brun Y V
Abstract excerpt
FtsZ is required throughout the cell division process in eubacteria and in archaea. We report the isolation of novel mutants of the FtsZ gene in Caulobacter crescentus. Clusters of charged amino acids were changed to alanine to minimize mutations that affect protein folding. Molecular modelling indicated that all the clustered-charged-to-alanine mutations had altered amino acids at the surface of the protein. Of...
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