A mutation in Escherichia coli ftsZ bypasses the requirement for the essential division gene zipA and confers resistance to FtsZ assembly inhibitors by stabilizing protofilament bundling.

Abstract excerpt

The earliest step in Escherichia coli cell division consists of the assembly of FtsZ protein into a proto-ring structure, tethered to the cytoplasmic membrane by FtsA and ZipA. The proto-ring then recruits additional cell division proteins to form the divisome. Previously we described an ftsZ all...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Carrier Proteins
• Share to Cell Cycle Proteins
• Share to Cell Division