Article
Paracrine mitogenic effect of human endothelial progenitor cells: role of interleukin-8.
American journal of physiology. Heart and circulatory physiology - 1 Aug 2005
He Tongrong, Peterson Timothy E, Katusic Zvonimir S
Abstract excerpt
Endothelial progenitor cells (EPCs) play an important role in repair of vascular injury and neovascularization. Molecular mechanisms underlying vascular effects of EPCs are not fully understood. The present study was designed to test the hypothesis that human EPCs exert a strong paracrine mitogenic effect on mature endothelial cells. Levels of interleukin-8 (IL-8) were significantly higher in conditioned medium...
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