Article
[Nasopharyngeal carcinomas: from biology to clinic].
Cancer radiotherapie : journal de la Societe francaise de radiotherapie oncologique - 1 Feb 2005
Rivera S, Keryer C, Busson P, Maingon P
Abstract excerpt
Nasopharyngeal carcinomas (NPC) are very different from other head and neck cancers because of their specific multifactorial etiology and their geographic distribution. Epstein-Barr Virus (EBV) is implicated in oncogenesis of NPC in association with genetic alterations such as inactivation of the p16/Ink4, p19/ARF, RASSF1 or Blu genes. Tumoral tissues include a very abundant characteristic lymphoid infiltrate....
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