Article
Nasopharyngeal carcinoma--review of the molecular mechanisms of tumorigenesis.
Head & neck - 1 Jul 2008
Chou Josephine, Lin Yu-Ching, Kim Jae, You Liang, Xu Zhidong, He Biao, Jablons David M
Abstract excerpt
Nasopharyngeal carcinoma (NPC) is a head and neck cancer rare throughout most of the world but common in certain geographic areas, such as southern Asia. While environmental factors and genetic susceptibility play important roles in NPC pathogenesis, the Epstein-Barr virus in particular has been implicated in the molecular abnormalities leading to NPC. There is upregulation of cellular proliferation pathways such...
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