Article
Genetic variation in the sand fly salivary protein, SP-15, a potential vaccine candidate against Leishmania major.
Insect molecular biology - 1 Apr 2005
Elnaiem D-E A, Meneses C, Slotman M, Lanzaro G C
Abstract excerpt
SP-15 is a sandfly salivary protein that provides strong protection against cutaneous leishmaniasis, caused by Leishmania major, and has been proposed as a potential vaccine against this disease. To investigate possible antigenic variation in this protein, we examined genetic polymorphism of SP-15 in 100 Phlebotomus papatasi sandflies, from a natural population from Sudan and four laboratory colonies from Egypt,...
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