Article
End-diastolic myofiber stress and ejection strain increase with ventricular volume overload--Serial in-vivo analyses in dogs with complete atrioventricular block.
Basic research in cardiology - 1 Jul 2005
Donker D W, Volders P G A, Arts T, Bekkers B C A M, Hofstra L, Spätjens R L H M G, Beekman J D M, Borgers M, Crijns H J G M, Vos M A
Abstract excerpt
BACKGROUND: Myocardial stress and strain are considered primary mechanical stimuli for hypertrophic remodeling. Their values and significance in the intact beating heart during chronic overload remain poorly characterized. METHODS AND RESULTS: Left-ventricular (LV) dimensions (echocardiography) and pressure (invasive) were simultaneously recorded in anesthetized dogs at sinus rhythm (SR), acute and 1, 2, 6, 12...
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