Aminoacyl-tRNA synthetase-induced cleavage of tRNA.

doi:10.1093/nar/20.7.1523

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Article

Aminoacyl-tRNA synthetase-induced cleavage of tRNA.

Nucleic acids research - 11 Apr 1992

Beresten S, Jahn M, Söll D

Abstract excerpt

Aminoacyl-tRNA synthetases interact with their cognate tRNAs in a highly specific fashion. We have examined the phenomenon that upon complex formation E. coli glutaminyl-tRNA synthetase destabilizes tRNA(Gln) causing chain scissions in the presence of Mg2+ ions. The phosphodiester bond cleavage p...

Topics

Amino Acyl-tRNA Synthetases
Base Sequence
Escherichia coli
Kinetics
Magnesium
Molecular Sequence Data
Mutation
Nucleic Acid Conformation
RNA, Transfer, Gln
RNA, Transfer, Trp

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