Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Collagen alpha1(I) gene (COL1A1) is repressed by RFX family.

The Journal of biological chemistry - 3 Jun 2005

Sengupta Pritam, Xu Yong, Wang Lin, Widom Russell, Smith Barbara D

Abstract excerpt

Collagen type I is composed of three polypeptide chains transcribed from two separate genes (COL1A1 and COL1A2) with different promoters requiring coordinate regulation. Our recent publications, centering on COL1A2 regulation, demonstrate that methylation in the first exon of COL1A2 at a regulatory factor for X box (RFX) site (at -1 to +20) occurs in human cancer cells and correlates with increased RFX1 binding...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Lentivirus
Share to Azacitidine
Share to Collagen

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Collagen Type I

Share to Collagen Type I, alpha 1 Chain

Share to Fibrosarcoma

Share to Regulatory Factor X Transcription Factors

Share to Sulfites

Source

Open in PubMed Open full text

Identifiers

PMID: 15788405
DOI: 10.1074/jbc.M413191200
PMCID: PMC1382295

Genes

CIITA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Collagen alpha1(I) gene (COL1A1) is repressed by RFX family.PMID 15788405Read ↗

Interferon γ Repression of Collagen (COL1A2) Transcription Is Mediated by the RFX5 ComplexSemantic proximity Read ↗

A methylation-responsive MDBP/RFX site is in the first exon of the collagen alpha2(I) promoter.Semantic proximity Read ↗

Reviewing the Regulators of COL1A1Semantic proximity Read ↗

A gene encoding a novel RFX-associated transactivator is mutated in the majority of MHC class II deficiency patients.Semantic proximity Read ↗

RFX1, a Transactivator of Hepatitis B Virus Enhancer I, Belongs to a Novel Family of Homodimeric and Heterodimeric DNA-Binding ProteinsSemantic proximity Read ↗

RFX1, a transactivator of hepatitis B virus enhancer I, belongs to a novel family of homodimeric and heterodimeric DNA-binding proteins.Semantic proximity Read ↗

Interferon-γ Induces Major Histocompatibility Class II Transactivator (CIITA), Which Mediates Collagen Repression and Major Histocompatibility Class II Activation by Human Aortic Smooth Muscle CellsSemantic proximity Read ↗

Structure of the human type XIX collagen (COL19A1) gene, which suggests it has arisen from an ancestor gene of the FACIT family.Semantic proximity Read ↗

RFXB and its splice variant RFXBSV mediate the antagonism between IFNγ and TGFβ on COL1A2 transcription in vascular smooth muscle cellsSemantic proximity Read ↗

Transcriptional regulation of the COL1A2 gene in fibroblastsSemantic proximity Read ↗

RFXAP, a novel subunit of the RFX DNA binding complex is mutated in MHC class II deficiency.Semantic proximity Read ↗

The transcription factor RFX5 is a transcriptional activator of the TPP1 gene in hepatocellular carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.