Article
Multiple mutations and gene duplications conferring organophosphorus insecticide resistance have been selected at the Rop-1 locus of the sheep blowfly, Lucilia cuprina.
Journal of molecular evolution - 1 Feb 2005
Newcomb Richard D, Gleeson Dianne M, Yong Catherine G, Russell Robyn J, Oakeshott John G
Abstract excerpt
Sequences of the esterase gene alpha E7 were compared across 41 isogenic (IV) strains of the sheep blowfly, Lucilia cuprina, and one strain of the sibling species, L. sericata. The 1.2-kb region sequenced includes sites of two insecticide resistance mutations. Gly137Asp confers resistance to organophosphorus insecticides (OPs), particularly preferring diethyl OPs such as diazinon, while Trp251Leu prefers dimethyl...
Topics
- Animals
- Base Sequence
- DNA
- Diptera
- Esterases
- Evolution, Molecular
- Gene Duplication
- Genes, Insect
- Insecticide Resistance
- Molecular Sequence Data
- Mutation
- Phylogeny
- Sequence Homology, Nucleic Acid
- Sheep