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Article

The theoretical underpinnings of affective temperaments: implications for evolutionary foundations of bipolar disorder and human nature.

Journal of affective disorders - 1 Mar 2005

Akiskal Kareen K, Akiskal Hagop S

Abstract excerpt

We sketch out putative evolutionary roles for affective temperaments within the theoretical framework of mood disorders conceptualized as extremes in an oligogenic model of inheritance, whereby the constituent traits in their dilute phenotypes confer adaptive advantages to individuals and/or their social group. Depressive traits, among other functions, would subserve sensitivity to the suffering of other members...

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Identifiers

PMID: 15780693
DOI: 10.1016/j.jad.2004.08.002

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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