Article
High relative content of lysophospholipids of Helicobacter pylori mediates increased risk for ulcer disease.
FEMS immunology and medical microbiology - 1 Apr 2005
Tannaes Tone, Bukholm Ida K, Bukholm Geir
Abstract excerpt
Helicobacter pylori phospholipase A (OMPLA) degrades bacterial membrane phospholipids to lysophospholipids. High levels of lysophospholipids are associated with higher hemolytic activity, increased release of urease and vacA and better adherence to epithelial cells in vitro. The phospholipase A gene (pldA) displays phase variation due to a slippage in a homopolymeric tract. The aim of this study was to determine...
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