Article
Characterization of Helicobacter pylori PldA, a phospholipase with a role in colonization of the gastric mucosa.
Gastroenterology - 1 Nov 1999
Dorrell N, Martino M C, Stabler R A, Ward S J, Zhang Z W, McColm A A, Farthing M J, Wren B W
Abstract excerpt
BACKGROUND & AIMS: Phospholipase activity may play a role in the pathogenicity of Helicobacter pylori. Furthermore, some drugs that are effective against H. pylori infection are phospholipase inhibitors. Scrutiny of the H. pylori 26695 genome sequence revealed the presence of a putative protein with homology to Esherichia coli outer membrane phospholipase A (PldA). The aim of this study was to investigate the...
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