Article
Pivotal role of AtSUVH2 in heterochromatic histone methylation and gene silencing in Arabidopsis.
The EMBO journal - 6 Apr 2005
Naumann Kathrin, Fischer Andreas, Hofmann Ingo, Krauss Veiko, Phalke Sameer, Irmler Kristina, Hause Gerd, Aurich Anne-Cathleen, Dorn Rainer, Jenuwein Thomas, Reuter Gunter
Abstract excerpt
SU(VAR)3-9 like histone methyltransferases control heterochromatic domains in eukaryotes. In Arabidopsis, 10 SUVH genes encode SU(VAR)3-9 homologues where SUVH1, SUVH2 and SUVH4 (KRYPTONITE) represent distinct subgroups of SUVH genes. Loss of SUVH1 and SUVH4 causes weak reduction of heterochromatic histone H3K9 dimethylation, whereas in SUVH2 null plants mono- and dimethyl H3K9, mono- and dimethyl H3K27, and...
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