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Article

Founder mutation in familial adenomatous polyposis (FAP) in the Balearic Islands.

Cancer genetics and cytogenetics - 1 Apr 2005

González Sara, Blanco Ignacio, Campos Olga, Julià María, Reyes José, Llompart Alfred, Cabeza Elena, Germà Josep Ramon, Obrador Antoni, Capellá Gabriel

Abstract excerpt

The incidence of familial adenomatous polyposis (FAP) is approximately 7.4 per 100,000 inhabitants. APC gene mutations have been found in 60-70% of all FAP families, codons 1309 (20%) and 1061 (8%) being known hot-spots. We searched for mutations in the APC gene in a population-based registry of FAP from the Spanish Balearic Islands. Fifty-one members of 12 FAP families registered in the Balearic Islands Cancer...

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Identifiers

PMID: 15771908
DOI: 10.1016/j.cancergencyto.2004.07.003

Genes

FAP
APC

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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