Association analysis between novel variants in LEPR gene and litter size in Mongolia and ujimqin sheep breeds.

doi:10.1016/j.theriogenology.2022.02.014

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Article

Association analysis between novel variants in LEPR gene and litter size in Mongolia and ujimqin sheep breeds.

Theriogenology - 15 Apr 2022

Ma Shujiao, Ji Xuewen, Cang Ming, Wang Jianguo, Yu Haiquan, Liu Yongbin, Zhang Wenguang, Wu Yiran, Zhao Suwen, Cao Guifang, Tong Bin

Abstract excerpt

Prolificacy is an important trait of livestock, especially for species with multiple births, such as sheep. The leptin receptor (LEPR) is considered as a major candidate gene that affects the reproductive traits of sheep. The known R62H mutation in the LEPR gene is associated with the hyperprolific phenotype of Davisdale sheep. However, studies identifying novel variations and seeking breed-specific markers...

Topics

Animals
Female
Genotype
Litter Size
Mongolia
Phenotype
Polymorphism, Single Nucleotide
Pregnancy
Sheep

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Identifiers

PMID: 35228133
DOI: 10.1016/j.theriogenology.2022.02.014

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