Article
Bacterial multidrug resistance unrelated to multidrug exporters: cell biology insight.
Cell biology international - 1 Jan 2005
Cherepenko Yelena, Hovorun Dmytro M
Abstract excerpt
Multidrug resistance (MDR) revealed in malignant cell lines was firstly attributed to the activity of multidrug exporters pumping drugs out of the cell. However, mutagenised Escherichia coli develop extraordinary numerous mutants resistant to target inhibitor and we have shown that with mutations mapped around the entire genome most of the mutants were multiple-resistant. In case of one such mutant studied MDR...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
