Molecular regulation of hepatobiliary transport systems: clinical implications for understanding and treating cholestasis.

Abstract excerpt

Hepatobiliary transport systems are responsible for hepatic uptake and excretion of bile salts and other biliary constituents (eg, bilirubin) into bile. Hereditary transport defects can result in progressive familial and benign recurrent intrahepatic cholestasis. Exposure to acquired cholestatic injury (eg, drugs, hormones, proinflammatory cytokines, biliary obstruction or destruction) also results in altered...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Bile
• Share to Bile Acids and Salts
• Share to Biological Transport, Active