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Selection of tumor-targeting agents on freshly excised human breast tumors using a phage display library

1 Apr 2005

Abstract excerpt

The selective delivery of therapeutic agents to tumor site without harming rest of the body is a major challenge in clinical oncology today. Phage display approach has been used for searching ligands for cell-surface macromolecules on cancer cells so that they can be employed as drug targeting agents. Although basic protocols for biopanning cells are available, they are not as such suitable for screening highly...

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PMID: 15756454
DOI: 10.3892/or.13.4.757

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