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Identification of tumor‐associated antigens by screening phage‐displayed human cDNA libraries with sera from tumor patients

5 Jun 2003

Abstract excerpt

Screening cDNA libraries from solid human tumors with sera of autologous patients (SEREX) has proven to be a powerful approach to identifying tumor antigens recognized by the humoral arm of the immune system. In many cases, application of this methodology has led to the discovery of novel tumor antigens as unknown gene products. We tried to improve the potency of the SEREX approach by combining it with...

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PMID: 12845649
DOI: 10.1002/ijc.11269

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