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Article

Patterns of human diversity, within and among continents, inferred from biallelic DNA polymorphisms.

Genome research - 1 Apr 2002

Romualdi Chiara, Balding David, Nasidze Ivane S, Risch Gregory, Robichaux Myles, Sherry Stephen T, Stoneking Mark, Batzer Mark A, Barbujani Guido

Abstract excerpt

Previous studies have reported that about 85% of human diversity at Short Tandem Repeat (STR) and Restriction Fragment Length Polymorphism (RFLP) autosomal loci is due to differences between individuals of the same population, whereas differences among continental groups account for only 10% of the overall genetic variance. These findings conflict with popular notions of distinct and relatively homogeneous human...

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Identifiers

PMID: 11932244
DOI: 10.1101/gr.214902
PMCID: PMC187513

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