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Article

Towards a new interaction enzyme:coenzyme.

Biophysical chemistry - 1 Apr 2005

Martínez-Júlvez Marta, Tejero Jesús, Peregrina José R, Nogués Isabel, Frago Susana, Gómez-Moreno Carlos, Medina Milagros

Abstract excerpt

Ferredoxin-NADP(+) reductase catalyses NADP(+) reduction, being specific for NADP(+)/H. To understand coenzyme specificity determinants and coenzyme specificity reversion, mutations at the NADP(+)/H pyrophosphate binding and of the C-terminal regions have been simultaneously introduced in Anabaena FNR. The T155G/A160T/L263P/Y303S mutant was produced. The mutated enzyme presents similar k(cat) values for NADPH and...

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Identifiers

PMID: 15752608
DOI: 10.1016/j.bpc.2004.12.034

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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