Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of humanin on decreased ATP levels of human lymphocytes harboring A3243G mutant mitochondrial DNA.

Neuropeptides - 1 Apr 2005

Kariya Shingo, Hirano Makito, Furiya Yoshiko, Ueno Satoshi

Abstract excerpt

Humanin (HN) was originally identified as an endogenous peptide that protects neuronal cells from apoptosis by mutant Alzheimer's disease genes. This 24-residue peptide has been recently shown to suppress apoptosis by interfering with activation of Bcl-2-associated X protein (Bax) in cytosol. In the present study, we showed that HN increases ATP levels in human lymphocytes, muscular TE671 cells, and neural SKN-MC...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenosine Triphosphate
Share to Apoptosis
Share to Cell Survival

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Intracellular Signaling Peptides and Proteins

Share to Lymphocytes

Share to MELAS Syndrome

Share to Muscles

Share to Proteins

Source

Identifiers

PMID: 15752543
DOI: 10.1016/j.npep.2004.11.004

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of humanin on decreased ATP levels of human lymphocytes harboring A3243G mutant mitochondrial DNA.PMID 15752543Read ↗

Humanin: A mitochondrial-derived peptide in the treatment of apoptosis-related diseasesSemantic proximity Read ↗

Naturally occurring mitochondrial-derived peptides are age-dependent regulators of apoptosis, insulin sensitivity, and inflammatory markersSemantic proximity Read ↗

Mitochondrial-derived peptide humanin as therapeutic target in cancer and degenerative diseasesSemantic proximity Read ↗

Neuroprotective Action of Humanin and Humanin Analogues: Research Findings and PerspectivesSemantic proximity Read ↗

The emerging role of the mitochondrial-derived peptide humanin in stress resistanceSemantic proximity Read ↗

Humanin and Age-Related Diseases: A New Link?Semantic proximity Read ↗

Effects of nitric oxide donors on cybrids harbouring the mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) A3243G mitochondrial DNA mutation.Semantic proximity Read ↗

Humanin inhibits cell death of serum-deprived PC12h cellsSemantic proximity Read ↗

Humanin: a harbinger of mitochondrial-derived peptides?Semantic proximity Read ↗

Mitochondrial-dependent apoptosis in Huntington's disease human cybridsSemantic proximity Read ↗

Pre-B-cell colony-enhancing factor exerts a neuronal protection through its enzymatic activity and the reduction of mitochondrial dysfunction in in vitro ischemic models.Semantic proximity Read ↗

Increased apoptosis, Huntingtin inclusions and altered differentiation in muscle cell cultures from Huntington's disease subjects.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.