Article
Targeted cancer therapies.
Bulletin du cancer - 1 Feb 2005
Blay Jean-Yves, Le Cesne Axel, Alberti Laurent, Ray-Coquart Isabelle
Abstract excerpt
The term "targeted cancer therapies" refers to treatment strategies designed to inhibit the product of an oncogene involved in the process of neoplastic transformation. Different categories of targeted therapies can be identified: 1) Therapies directed at oncogenes that are directly involved in the initiation of neoplastic transformation: the use of imatinib for the treatment of CML or GIST is the classical model...
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