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Targeted Therapies in Cancer: To Be or Not to Be, Selective

1 Nov 2021

Abstract excerpt

Development of targeted therapies in recent years revealed several nonchemotherapeutic options for patients. Chief among targeted therapies is small molecule kinase inhibitors targeting key oncogenic signaling proteins. Through competitive and noncompetitive inhibition of these kinases, and therefore the pathways they activate, cancers can be slowed or completely eradicated, leading to partial or complete...

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PMID: 34829820
DOI: 10.3390/biomedicines9111591

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