Major sex differences in non-genomic estrogen actions on intracellular signaling in mouse brain in vivo.

doi:10.1016/j.neuroscience.2004.10.046

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Article

Major sex differences in non-genomic estrogen actions on intracellular signaling in mouse brain in vivo.

Neuroscience - 1 Jan 2005

Abrahám I M, Herbison A E

Abstract excerpt

Rapid effects of estrogen have now been identified throughout the brain but the extent to which these actions may be different in males and females is unknown. Previous work has shown that estrogen rapidly phosphorylates Ser133 of cAMP responsive element binding protein (CREB) through a non-genomic mechanism. Using this indicator, we have examined here whether non-genomic estrogen actions occur in a sexually...

Topics

Animals
Brain
Brain Chemistry
Cyclic AMP Response Element-Binding Protein
Estradiol
Female
Gonadotropin-Releasing Hormone
Immunohistochemistry
Male
Mice
Mice, Inbred C57BL
Mice, Inbred CBA
Neurons
Orchiectomy
Ovariectomy
Phenotype
Phosphorylation
Sex Characteristics

Source

Open in PubMed

Identifiers

PMID: 15749347
DOI: 10.1016/j.neuroscience.2004.10.046

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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