Article
Fas polymorphisms are associated with the presence of anti-ganglioside antibodies in Guillain-Barre syndrome.
Journal of neuroimmunology - 1 Apr 2005
Geleijns Karin, Laman Jon D, van Rijs Wouter, Tio-Gillen Anne P, Hintzen Rogier Q, van Doorn Pieter A, Jacobs Bart C
Abstract excerpt
Polymorphisms in genes involved in regulation of immune homeostasis may be a susceptibility factor in the induction of cross-reactive anti-ganglioside antibodies after infection in patients with Guillain-Barre syndrome (GBS). In this study we assessed whether polymorphisms in the promoter region of Fas and FasL and sFas and sFasL are related to GBS or its distinct clinical or serological subgroups. We show that...
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