Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells.

Experimental cell research - 1 Apr 2005

Takada Eiko, Shimo Kuniaki, Hata Kikumi, Abiake Maira, Mukai Yasuo, Moriyama Masami, Heasley Lynn, Mizuguchi Junichiro

Abstract excerpt

Type I interferon (IFN)-induced antitumor action is due in part to apoptosis, but the molecular mechanisms underlying IFN-induced apoptosis remain largely unresolved. In the present study, we demonstrate that IFN-beta induced apoptosis and the loss of mitochondrial membrane potential (delta psi m...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to B-Lymphocytes
Share to Fas Ligand Protein
Share to fas Receptor

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Interferon-beta

Share to JNK Mitogen-Activated Protein Kinases

Share to Jurkat Cells

Share to Lymphoma, B-Cell

Share to Membrane Potentials

Source

Identifiers

PMID: 15748896
DOI: 10.1016/j.yexcr.2004.11.015

Genes

TNF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-15748896-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Interferon-beta-induced activation of c-Jun NH2-terminal kinase mediates apoptosis through up-regulation of CD95 in CH31 B lymphoma cells.PMID 15748896Read ↗

Interferons and ApoptosisSemantic proximity Read ↗

Interferon‑α and its effects on cancer cell apoptosis (Review)Semantic proximity Read ↗

Interferons as Inducers of Apoptosis in Malignant CellsSemantic proximity Read ↗

NF-kappaB inducers upregulate cFLIP, a cycloheximide-sensitive inhibitor of death receptor signaling.Semantic proximity Read ↗

Ceramide-induced apoptosis by translocation, phosphorylation, and activation of protein kinase Cdelta in the Golgi complex.Semantic proximity Read ↗

Activation of JNK-dependent pathway is required for HIV Viral Protein R-induced apoptosis in human monocytic cells. INVOLVEMENT OF ANTIAPOPTOTIC BCL2 AND c-IAP1 GENES.Semantic proximity Read ↗

Apoptotic Caspases Suppress mtDNA-Induced STING-Mediated Type I IFN ProductionSemantic proximity Read ↗

Interferon-γ Modulates a p53-independent Apoptotic Pathway and Apoptosis-related Gene ExpressionSemantic proximity Read ↗

Type I interferons are essential mediators of apoptotic death in virally infected cellsSemantic proximity Read ↗

T-bet transduction enhances anti-tumor efficacy of IFN-producing dendritic cell (IKDC) against hepatocellular carcinoma via apoptosis induction.Semantic proximity Read ↗

IFN-gammaupregulates apoptosis-related molecules and enhances Fas-mediated apoptosis in human cholangiocarcinoma.Semantic proximity Read ↗

Prevention of anti-IgM-induced apoptosis accompanying G1 arrest in B lymphoma cells overexpressing dominant-negative mutant form of c-Jun N-terminal kinase 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.