Analysis of the characteristics of epilepsy in 37 patients with the molecular diagnosis of Angelman syndrome

Abstract excerpt

Angelman syndrome is a genetic disorder caused by defects in the maternally inherited imprinted domain located on chromosome 15q11-q13. Most patients with Angelman syndrome present with severe mental retardation, characteristic physical appearance, behavioral traits, and severe, early-onset epilepsy. We retrospectively reviewed the medical histories of 37 patients, all with the molecular diagnosis of Angelman...

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• Share to Epigenetics and DNA Methylation
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