Article
Myeloid antigens in childhood lymphoblastic leukemia: clinical data point to regulation of CD66c distinct from other myeloid antigens.
BMC cancer - 12 Apr 2005
Kalina Tomas, Vaskova Martina, Mejstrikova Ester, Madzo Jozef, Trka Jan, Stary Jan, Hrusak Ondrej
Abstract excerpt
BACKGROUND: Aberrant expression of myeloid antigens (MyAgs) on acute lymphoblastic leukemia (ALL) cells is a well-documented phenomenon, although its regulating mechanisms are unclear. MyAgs in ALL are interpreted e.g. as hallmarks of early differentiation stage and/or lineage indecisiveness. Granulocytic marker CD66c -- Carcinoembryonic antigen-related cell adhesion molecule 6 (CEACAM6) is aberrantly expressed...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
