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Article

Complete mutation screening and haplotype characterization of the BRCA1 gene in 61 familial breast cancer patients from Norway.

Disease markers - 1 Jan 2005

Frost Petter, Jugessur Astanand, Apold Jaran, Heimdal Ketil, Aloysius Thomas, Eliassen Aud K, Fauske Lars, Matre Guri, Eiken Hans Geir

Abstract excerpt

Mutations in the Breast-Cancer-1 (BRCA1) gene are the major cause of familial breast/ovarian cancer. Among familial breast cancer only, 15-20% have been suggested to have a deleterious mutation in BRCA1. A highly sensitive method (REF-SSCP) was applied to screen the open reading frame and the 5'UTRs of BRCA1 for mutations. The patient cohort comprised 61 unrelated moderate to high risk breast cancer patients from...

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Source

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Identifiers

PMID: 15735322
DOI: 10.1155/2005/542928
PMCID: PMC3850610

Genes

BRCA1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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