Article
Impact of alphaENaC polymorphisms on the risk of ischemic cerebrovascular events: a multicenter case-control study.
Clinical chemistry - 1 Jun 2005
Hsieh Kety, Lalouschek Wolfgang, Schillinger Martin, Endler Georg, Reisinger Manuela, Janisiw Michael, Lang Wilfried, Cheng Suzanne, Wagner Oswald, Mannhalter Christine
Abstract excerpt
BACKGROUND: Amiloride-sensitive epithelial sodium channels (ENaCs) are important candidates in the development of hypertension, which is a major risk factor for stroke. Two single-nucleotide polymorphisms (SNPs) in the gene that encodes the ENac alpha-subunit (alphaENaC) have been identified. We...
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